This potent crème stimulates skin rejuvenation with a proprietary KemSpheres™ delivery system that allows the release of pure, encapsulated retinol into the skin with minimal irritation. This advanced technology exfoliates the surface layer of the skin and increases cellular turnover while supporting collagen production. This product should be slowly introduced into your skincare regime. Starting two night a week and working your way up to 7 nights a week. You will feel product working when you first apply it, redness and activity is normal and will dissipate after a few minutes.